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- January 19th, 2025
The mutations in human VPS11(C846G), zebrafish vps11(plt), and vps11(−/−) consequence in increasingly-truncated protein merchandise (Fig. 1). The missense mutation VPS11:C846G associated with gLE in human sufferers was predicted to disrupt its C-terminal RING-H2 area (Fig. 1). This area capabilities in estrogen receptor-α,...