Power Moves: KOP’s Center for Breakthrough Medicines has 4 new VPs, and a former Pfizer leader joins Spark

Power Moves is a column the place we chart the comings and goings of expertise throughout the area. Got a new rent, new gig or promotion? Email us: [email protected]

The (*4*), a cell and gene remedy contract developer and producer at King of Prussia’s Discovery Labs, mentioned this week it had added 4 ladies to its management crew. The appointments play a “important position in bringing the services on-line to ship actual options to superior remedy builders,” the org mentioned in a assertion.

Sybil Danby lately joined as SVP of enterprise growth and technique after spending three years working the strategic enterprise growth of Baltimore’s Paragon Bioservices and enjoying an lively position in its acquisition by Catalent Pharma Solutions for $1.2 billion in 2019.

“Advanced therapies are the way forward for medication, however their growth has been stalled by a lack of purposeful manufacturing options and capability. Unfortunately, present manufacturing applied sciences that do properly for giant molecule merchandise don’t all the time translate to cell and gene therapies,” Danby mentioned. “The Center for Breakthrough Medicines is in a distinctive place, and we’re working to fill these gaps for clients with the precise applied sciences and the capability to assist their wants.”

Eileen Brett joins the CBM as its VP of challenge management, bringing 20 years of end-to-end challenge administration and management expertise in biotherapeutics. She’s lately served as the pinnacle of the chemistry, manufacturing and controls leaders group for Janssen’s Biotherapeutics Development with duty for delivering the portfolio of biotherapeutic property from discovery to post-launch.

Newly appointed because the VP of testing and analytical providers is Dana Cipriano, who can be creating a testing and analytical providers portfolio that enables for environment friendly discovery, growth, commercialization and manufacturing of cell and gene remedy merchandise. She can be supplying end-to-end options for CBM shoppers and enabling their velocity to market, the org mentioned.

Lastly, Emily Moran joined the crew as its VP of viral vector manufacturing. She was lately the pinnacle of viral vector manufacturing at Switzerland-based chemical substances firm Lonza. Moran additionally spent 12 years with Sanofi in utilized operational and high quality roles.


University City gene remedy firm Spark Therapeutics lately introduced that it had appointed long-time life sciences exec Cynthia Pussinen as its chief technical officer.

Cynthia Pussinen. (Courtesy picture)

NYC-based Pussinen has beforehand lead groups in manufacturing, high quality, provide chain, formulation growth and processes sciences at corporations resembling Honeywell International, Inc., Actinium Pharmaceuticals, Inc. and Ipsen Biosciences.

Pussinen additionally spent greater than 18 years at Pfizer in several roles together with portfolio and challenge administration, logistics and provide chain, pharmaceutical sciences, and as a scientist in its medicinal chemistry. As Spark’s CTO, she’ll oversee the corporate’s manufacturing and technical operations.

“We are excited to welcome Cynthia to Spark, as she brings each the experience and management wanted to achieve success on this position,” Spark CEO Jeffrey Marrazzo mentioned in a assertion. “We are assured she can be a wonderful addition to our administration crew as we put together to convey ahead the following technology of gene therapies to sufferers.”

Pussinen mentioned she feels that gene therapies signify the current and future of medication, and that it’s an “honor” to hitch Spark, which added about 250 hires in 2020, a firm spokesperson mentioned. The firm now has about 600 workers. Spark’s $4.8 billion acquisition deal with Roche in 2019 ended up being the town’s largest-ever exit for a venture-backed firm.

“I love the Spark crew’s ardour for the essential position they play in delivering progressive gene therapies to sufferers, and I look ahead to becoming a member of the corporate and making an affect on these sufferers’ lives,” Pussinen mentioned in a assertion.


Tax expertise and providers platform Vertex, which relies in King of Prussia and has places of work in South America and Europe, introduced it had employed Sal Visca as its CTO this week.

Visca will lead the corporate’s tech technique, software program engineering and innovation because it accelerates development. The firm, which employs about 1,200 folks throughout a number of continents, went public in July 2020. It is the maker of cloud-based and on-premise tax instruments that may be personalized by trade.

Visca brings 30 years of tech expertise in reworking and working large-scale cloud software program companies. He beforehand served as CTO at Elastic Path Software, Business Objects and Infowave Software, in addition to serving as SVP and CTO of SAP’s Application and BI Platform Group.

“We got down to discover an distinctive, purpose-driven leader — somebody with that uncommon mixture of interpersonal abilities, technical savvy and an progressive spirit to run a modern expertise group — we’re lucky to welcome Sal to Vertex,” CEO David DeStefano mentioned in a assertion.


Margo DelliCarpini was named the chancellor and dean of Penn State Abington in January.

Margo DelliCarpini. (Courtesy picture)

Before becoming a member of Penn State Abington, DelliCarpini served as vice provost for strategic instructional partnerships and dean of the College of Education and Human Development at The University of Texas at San Antonio, and as professor and dean of the College of Education at Morehead State University in Kentucky.

Earlier in her profession, she taught at Lehman College of the City University of New York, first as an assistant professor in 2005, as affiliate professor in 2010, and full professor in 2013. She served because the chair of the division of center and highschool schooling over the past three years as professor.

DelliCarpini was additionally the editor for an award-winning, 14-volume reference collection, the “TESOL Encyclopedia of English” (Wiley, 2018).


The Chamber of Commerce for Greater Philadelphia has awarded Penn Mutual CEO and chairperson Eileen C. McDonnell with the 2021 Paradigm Award. The Chamber described the award as “the area’s most prestigious award for businesswomen.” McDonnell has been in her position since 2013.

“Eileen is considered one of our area’s most influential figures and represents our neighborhood of excellent enterprise leaders,” mentioned Chamber President and CEO Rob Wonderling. “She is a outstanding and inspirational leader with excellent private and skilled abilities. We are lucky to have such an distinctive government in our area.”


And this week, Philly Startup Leaders introduced that it had named Isabelle Kent as its new government director. She takes over the entrepreneurship-boosting nonprofit a few months after former ED Kiera Smalls left to run supply startup Bloc Delivery.

Read our profile of Kent and read her letter to the startup community.

Isabelle Kent. (Photo by way of LinkedIn)


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